… A phase I trial to determine the optimal biological dose of celecoxib when combined with
erlotinib in advanced non-small cell lung cancer. Clinical …

… Our recent study reported on the combination of Celecoxib … finding indicated an additive
mechanism of Celecoxib and … Citation2014), however, to the best of our knowledge, this is the …

… present study the majority of patients received a combination of a … is a maximum of 400 mg
per day, and that higher doses may … finding was obtained in a smaller phase II study for breast …

… Celecoxib was observed to induce lung cancer cell apoptosis … Our study also proved that
COX-2 inhibitors combined with first-… effectively reduce the risk of diarrhea caused by erlotinib. …

… of erlotinib combined celecoxib (EC) for the treatment of advanced non-small cell lung cancer
(ANSCLC), no study … [27] Another study established the optimal biological dose (OBD), and …

… study aimed to identify the radiosensitizing effect of celecoxib… combination with radiotherapy
in non-small-cell lung cancer (… Gy/min for 1 min; The maximum dosage of 6 Gy was selected …

… male with advanced non-small cell lung cancer EGFR M… phase I trial to determine the
optimal biological dose of celecoxib when combined with erlotinib in advanced nonsmall cell lung …

… From this biological rationale, although more toxic, the combination … The erlotinib–celecoxib
combination also increases radiation … In addition, it is necessary to determine the best way to …

… of cisplatin in first-line combination regimens for NSCLC, the issues … biological therapy.
The non-selective application of EGFR tyrosine kinase inhibitors such as gefitinib and erlotinib …

… It is being used in combination with other drugs for the … Erlotinib, like gefitinib, is a small
molecular agent that is used to target … strongly inhibit cell growth than celecoxib [138]. In addition, …